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Let’s get the facts straight about endocrine disruptors before jumping to conclusions

Environmental News Network reported this week that the Center for Biological Diversity has petitioned the U.S. Environmental Protection Agency (EPA) to “regulate chemicals that pose widespread risk to human and animal reproduction.” A Center advocate wrongly claims in the article that “drinking water and aquatic habitat for wildlife is being increasingly and unnecessarily contaminated by endocrine disruptors such as pesticides and pharmaceuticals.”

Entire product categories such as pesticides and pharmaceuticals are not endocrine disruptors.  EPA’s Endocrine Disruptors Screening Program (EDSP), which began late last year, will help determine whether specified chemicals within pesticide products have the potential to be endocrine disruptors that could possibly impact human health or wildlife.

Member companies of the Consumer Specialty Products Association have received test orders required under EDSP from EPA and are in the process of complying with the program. They are reviewing existing internal and external data files and will be determining what additional data they need to generate for individual company responses to EPA.

There is no “regulatory void for controlling endocrine disruptors,” as claimed by the representative from the Center for Biological Diversity.   There is, however, a scientific gap that EPA has been working to fill.  As mandated by Congress, EPA has developed the EDSP to include a rigorous million-dollar battery of tests to look at the potential for endocrine disruption by chemicals, the results from which could trigger many millions of dollars of animal testing to determine whether the potential endocrine effects might lead to impacts on human health or wildlife.  It is important to understand that endocrine modulation is not a toxicological endpoint, but rather a toxicological mechanism that could lead to toxicological impacts.

No conclusions can be drawn yet about what chemicals might be endocrine disruptors, nor  should entire product categories be condemned as such.  Neither can we say yet whether any man-made environmental chemicals (there are many natural chemicals that appear to be endocrine disruptors, such as phytoestrogens) are having toxicological impacts through endocrine mechanisms.  Let’s give the EPA some time to implement the EDSP before jumping to conclusions.

Doug Fratz, CSPA Vice President, Scientific and Technical Affairs

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